Rat CTR CHO
CBP71646
詢(xún) 價(jià)
索取protocol
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| I. Background | |
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大鼠 CTR（Calcitonin Receptor，降鈣素受體），是位于 4 號(hào)染色體上的 Class B G 蛋白偶聯(lián)受體，高親和力結(jié)合降鈣素（Calcitonin），通過(guò) Gs/Gq 激活 cAMP 和 Ca²? 通路，主要分布于破骨細(xì)胞、腎及腦，參與鈣磷穩(wěn)態(tài)調(diào)節(jié)和骨吸收抑制。 |
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| II. Description | |
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Rat CTR CHO 細(xì)胞，在 CHO 細(xì)胞的基礎(chǔ)上，穩(wěn)定表達(dá)Rat CTR。 |
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| III. Introduction | |
| Expressed gene: | Rat CTR |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K + 10%FBS + 5μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional assay for Rat CTR |
| Transducer: | Gs |
IV. Representative Data Figure 1. HTRF cAMP Assay with Rat CTR CHO(C22). |
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