Mouse CTR COS7
CBP71641
詢 價
索取protocol
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
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小鼠CTR(降鈣素受體,Calcitonin Receptor)是由Calcr基因編碼的B類G蛋白偶聯(lián)受體,在不僅是降鈣素的內(nèi)源性受體,還能與RAMPs蛋白家族成員結(jié)合,形成對胰淀素(amylin)和CGRP等配體具有不同親和力的多種受體復(fù)合物。 小鼠CTR的藥理學(xué)特性與人類受體存在顯著差異,其對不同配體的選擇性較低,表現(xiàn)為一種“廣譜”特性。 |
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| II. Description | |
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Mouse CTR COS7 細胞,在 COS7 細胞的基礎(chǔ)上,穩(wěn)定表達Mouse CTR。 |
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| III. Introduction | |
| Expressed gene: | Mouse CTR |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM + 10%FBS + 2μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional assay for Mouse CTR |
| Transducer: | Gs |
IV. Representative Data![]() Figure 1. HTRF cAMP Assay with Mouse CTR COS7(C78). |
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