hCD36/MC-38
CBPG0272
詢 價
留 言
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| I. Background | |
| CD36 是一種跨膜糖蛋白，屬于B類清道夫受體家族，廣泛表達于巨噬細胞、脂肪細胞、心肌細胞、血小板等多種細胞表面。它的主要功能包括識別和轉(zhuǎn)運長鏈脂肪酸（參與脂質(zhì)代謝與能量供應(yīng)）、介導(dǎo)巨噬細胞吞噬氧化低密度脂蛋白（oxLDL）從而促進泡沫細胞形成（動脈粥樣硬化的關(guān)鍵步驟），同時在免疫應(yīng)答中識別凋亡細胞和病原體。CD36 功能異常與脂代謝紊亂、胰島素抵抗、心血管疾病及阿爾茨海默病等病理狀態(tài)密切相關(guān)。 | |
| II. Introduction | |
| Host Cell: | MC-38 |
| Expressed gene: | hCD36 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Mus musculus, mouse |
| Tissue: | Colon |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| IV. Representative Data | |
|
|
|
