STEAP1 HEK293
CBP74584
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產(chǎn)品描述
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| I. Background | |
| STEAP1（Six Transmembrane Epithelial Antigen of the Prostate 1，前列腺癌六次跨膜上皮抗原1）定位于人染色體 7q21.13，編碼細(xì)胞膜上的六次跨膜蛋白，屬 STEAP 金屬氧化還原酶家族。它主要表達(dá)于前列腺、膀胱等組織及多種腫瘤細(xì)胞（前列腺癌、膀胱癌、尤文肉瘤等），定位于質(zhì)膜及細(xì)胞間連接處，具鐵/銅金屬離子還原活性，參與金屬離子轉(zhuǎn)運(yùn)與細(xì)胞間通訊，是腫瘤 ADC（抗體偶聯(lián)藥物）熱門靶點(diǎn)。 | |
| II. Description | |
| STEAP1 HEK293細(xì)胞，在 HEK293細(xì)胞的基礎(chǔ)上，穩(wěn)定表達(dá) STEAP1 。 | |
| III. Introduction | |
| Expressed gene: | STEAP1 |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant STEAP1 HEK293 constitutively expressing STEAP1. |
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