CEACAM5 HEK293
CBP74582
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產(chǎn)品描述
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| I. Background | |
| CEACAM5(癌胚抗原相關細胞黏附分子5),也就是大家常說的癌胚抗原(CEA),是由CEACAM5基因編碼的一種糖蛋白。 它在正常的成人組織中表達量很低,但在多種上皮性腫瘤(尤其是結直腸癌、胃癌、胰腺癌和肺癌)中會顯著高表達。由于它容易從腫瘤細胞表面脫落進入血液,所以血清CEA水平是臨床上廣泛使用的腫瘤標志物,主要用于癌癥的輔助診斷、療效監(jiān)測和復發(fā)監(jiān)測。在功能上,它作為細胞黏附分子參與腫瘤細胞的黏附、轉(zhuǎn)移和免疫逃逸,因此也是一個重要的治療靶點。 | |
| II. Description | |
| CEACAM5 HEK293細胞,在 HEK293細胞的基礎上,穩(wěn)定表達 CEACAM5 。 | |
| III. Introduction | |
| Expressed gene: | CEACAM5 |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
![]() Figure 1. Recombinant CEACAM5 HEK293 constitutively expressing CEACAM5. |
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